Yamamoto M, Fujimori R, Adachi K, Ito T, Kamimura K
Tohoku J Exp Med. 1975 Feb;115(2):197-8. doi: 10.1620/tjem.115.197.
Chromosome analysis was made in induced abortions within 12 gestational weeks after the first day of the last menstrual period. There were 22 cases (7.3%) of gross chromosome anomalies in 300 materials. About a half of aberrant embryos were born to mothers who had positive histories of drug treatments or X-irradiation for various reasons.
对末次月经首日起12孕周内人工流产的胚胎进行了染色体分析。300份样本中有22例(7.3%)存在明显的染色体异常。约半数异常胚胎的母亲曾因各种原因有过药物治疗或X线照射史。