Rowin J, Meriggioli M N, Cochran E J
Section of Neuromuscular Disease, Department of Neurological Sciences, Rush University, Chicago, IL, USA.
Neuromuscul Disord. 2001 Apr;11(3):305-8. doi: 10.1016/s0960-8966(00)00202-9.
Monomelic amyotrophy is a sporadic juvenile-onset disease that presents with gradual onset of weakness and atrophy in the hand muscles unilaterally. Generally, this disease is considered a 'benign' and non-progressive motor neuron disease, which stabilizes within five years of onset. We discuss a case that illustrates that monomelic amyotrophy may rarely exhibit late clinical progression to the lower extremities after a prolonged period of disease stability.
