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未成熟和成熟根尖切除牙齿冷冻保存及自体移植后的血管再生

Revascularization after cryopreservation and autotransplantation of immature and mature apicoectomized teeth.

作者信息

Laureys W, Beele H, Cornelissen R, Dermaut L

机构信息

Department of Orthodontics, University of Gent, Belgium.

出版信息

Am J Orthod Dentofacial Orthop. 2001 Apr;119(4):346-52. doi: 10.1067/mod.2001.113259.

Abstract

Autotransplantation of immature teeth can have a success rate of almost 98% if the tooth is atraumatically transplanted from the donor site to a suitable acceptor site and the extraoral time is kept to a minimum. When the tooth cannot be transplanted immediately, cryopreservation and storage in a tooth bank offer new possibilities for autotransplantation. However, the effect of cryopreservation on the revascularization of transplanted teeth is still unknown. The purpose of this study was to examine revascularization in immature teeth that have an open apex and in mature teeth that have had the apex cut. The study was carried out on 16 teeth in 2 dogs; 8 teeth were removed and immediately transplanted to the contralateral position and 8 teeth were cryopreserved and transplanted 1 week later. The results show that: (1) teeth can revascularize after autotransplantation if the original pulp tissue is removed at the time of extraction, (2) there is no significant difference in the amount of revascularization between teeth stored in a tooth bank for 7 days and those immediately transplanted without freezing, and (3) there is no difference in the ingrowth of new pulpal tissue between mature apicoectomized teeth and immature teeth.

摘要

如果未成熟牙齿在无创伤情况下从供体部位移植到合适的受体部位,且口外时间保持最短,自体移植成功率可达近98%。当牙齿无法立即移植时,冷冻保存和储存在牙库为自体移植提供了新的可能性。然而,冷冻保存对移植牙齿血管再生的影响仍不清楚。本研究的目的是检查根尖开放的未成熟牙齿和根尖已切除的成熟牙齿的血管再生情况。该研究在2只狗的16颗牙齿上进行;8颗牙齿被拔除并立即移植到对侧位置,8颗牙齿被冷冻保存并在1周后移植。结果表明:(1) 如果在拔牙时去除原牙髓组织,牙齿自体移植后可以实现血管再生;(2) 在牙库中保存7天的牙齿与未冷冻立即移植的牙齿之间,血管再生量没有显著差异;(3) 成熟的根尖切除牙齿和未成熟牙齿之间,新牙髓组织的长入没有差异。

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