Nagamoto A, Kijima H, Tsuchida T, Nomura S, Kumagai H
Department of Urology, Yamato Municipal Hospital, Kanagawa, 242-8602, Japan.
Anticancer Res. 2001 Jan-Feb;21(1B):567-70.
Recently, cases of collecting duct carcinoma have been reported which were thought to have arisen from the renal collecting ducts or distal tubuli. We present here a rare case of collecting duct carcinoma mixed with common (conventional) renal cell carcinoma. A 51-year-old man underwent right nephrectomy under the diagnosis of renal tumor. Histochemically, markers for the collecting ducts/distal tubuli, such as peanut agglutinin (PNA) and soybean agglutinin (SBA), were identified in the collecting duct carcinoma as well as on several luminar surfaces of the common renal cell carcinoma. Based on the results of histological, histochemical and chromosomal examinations, we speculated on the histogenesis of this collecting duct carcinoma.
最近，有报道称出现了被认为起源于肾集合管或远曲小管的集合管癌病例。我们在此呈现一例罕见的集合管癌合并普通（传统）肾细胞癌的病例。一名51岁男性在被诊断为肾肿瘤后接受了右肾切除术。组织化学检查发现，在集合管癌以及普通肾细胞癌的几个管腔表面均检测到了集合管/远曲小管标志物，如花生凝集素（PNA）和大豆凝集素（SBA）。基于组织学、组织化学和染色体检查结果，我们推测了该集合管癌的组织发生。
