Nagler R M, Laufer D
Department of Oral and Maxillofacial Surgery, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Anticancer Res. 2001 Jan-Feb;21(1B):759-64.
Basal cell carcinoma (BCC) is a locally invasive neoplasm, rarely metastatic, yet capable of significant local destruction and disfigurement. Invasion into the bone is uncommon and only a few cases of invasion into facial bones, but never to the mandible or maxilla, have been described. We report three patients with BCC lesions invading their jaws, as a consequence of which either their mandible or maxilla had to be partially resected. This resulted in facial mutilation which required comprehensive multi-disciplinary therapy to restore function and esthetics. Such therapy requires a combination of modalities offered by both plastic and maxillofacial surgeons, as well as oral and dental rehabilitators.
基底细胞癌（BCC）是一种局部侵袭性肿瘤，很少发生转移，但能够造成严重的局部破坏和毁容。侵犯骨骼的情况并不常见，仅有少数侵犯面骨的病例报道，但从未有侵犯下颌骨或上颌骨的病例。我们报告了3例基底细胞癌侵犯颌骨的患者，因此不得不对其下颌骨或上颌骨进行部分切除。这导致了面部毁容，需要综合多学科治疗来恢复功能和美观。这种治疗需要整形外科医生、颌面外科医生以及口腔和牙齿修复专家提供的多种治疗方式相结合。
