Solid-phase synthesis of N-acyl-N'-alkyl/aryl disubstituted guanidines.

作者信息

Ghosh A K, Hol W G, Fan E

机构信息

Department of Biological Structure and Biomolecular Structure Center, and Howard Hughes Medical Institute, University of Washington, Box 357742, Seattle, Washington 98195-7742, USA.

出版信息

J Org Chem. 2001 Mar 23;66(6):2161-4. doi: 10.1021/jo001420+.

DOI:10.1021/jo001420+

PMID:11300917

Abstract

摘要

相似文献

Solid-phase synthesis of N-acyl-N'-alkyl/aryl disubstituted guanidines.

J Org Chem. 2001 Mar 23;66(6):2161-4. doi: 10.1021/jo001420+.

A novel traceless resin-bound guanidinylating reagent for secondary amines to prepare N,N-disubstituted guanidines.

Org Lett. 2001 Apr 19;3(8):1133-6. doi: 10.1021/ol015576n.

Copper-catalyzed guanidinylation of aryl iodides: the formation of N,N'-disubstituted guanidines.

Org Lett. 2010 Mar 19;12(6):1316-9. doi: 10.1021/ol1002175.

A synthetic method to access symmetric and non-symmetric 2-(N,N'-disubstituted)guanidinebenzothiazoles.

Molecules. 2012 Aug 24;17(9):10178-91. doi: 10.3390/molecules170910178.

Combinatorial synthesis of heterocycles: solid-phase synthesis of 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine derivatives.

J Comb Chem. 2001 May-Jun;3(3):278-83. doi: 10.1021/cc000091w.

TFA-sensitive arylsulfonylthiourea-assisted synthesis of N,N'-substituted guanidines.

J Org Chem. 2003 Feb 21;68(4):1611-4. doi: 10.1021/jo026807m.

Solid-phase and solution-phase syntheses of oligomeric guanidines bearing peptide side chains.

J Org Chem. 2005 Oct 28;70(22):8801-10. doi: 10.1021/jo051226t.

Substituted guanidines: introducing diversity in combinatorial chemistry.

Org Lett. 2000 Nov 16;2(23):3539-42. doi: 10.1021/ol006322p.

Synthesis of symmetrical and unsymmetrical N,N'-diaryl guanidines via copper/N-methylglycine-catalyzed arylation of guanidine nitrate.

J Org Chem. 2012 Jun 15;77(12):5449-53. doi: 10.1021/jo300840x. Epub 2012 Jun 7.

Copper-catalyzed oxidative three-component synthesis of N, N',N″-trisubstituted guanidines.

Org Lett. 2013 Dec 20;15(24):6124-7. doi: 10.1021/ol4029622. Epub 2013 Nov 22.

引用本文的文献

Preparation of Mono-Cbz Protected Guanidines.

Organic Synth. 2015;92:91-102. doi: 10.15227/orgsyn.092.0091.

A synthetic method to access symmetric and non-symmetric 2-(N,N'-disubstituted)guanidinebenzothiazoles.

Molecules. 2012 Aug 24;17(9):10178-91. doi: 10.3390/molecules170910178.

Chlorotrimethylsilane activation of acylcyanamides for the synthesis of mono-N-acylguanidines.

J Org Chem. 2011 Aug 19;76(16):6967-71. doi: 10.1021/jo201264j. Epub 2011 Jul 19.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验