儿童服用洛哌丁胺的情况。

Lomotil ingestions in children.

作者信息

Wasserman G S, Green V A, Wise G W

出版信息

Am Fam Physician. 1975 Jun;11(6):93-7.

Abstract

Although the incidence of adverse reactions is relatively low in adults, Lomotil may result in serious toxicity in children. Early effects are often due to the atropine present in the compound, while the narcotic-like actions of diphenoxylate HCI tend to occur later. Respiratory depression is the most threatening reaction and should be treated with naloxone.

摘要

尽管成人中不良反应的发生率相对较低，但洛哌丁胺可能会对儿童造成严重毒性。早期影响通常是由于该化合物中含有的阿托品，而盐酸地芬诺酯的类麻醉作用往往在后期出现。呼吸抑制是最具威胁性的反应，应使用纳洛酮进行治疗。