Barrand K R, Scudamore C L
Fenwold Veterinary Group, Skegness, Lincolnshire.
J Small Anim Pract. 2001 Mar;42(3):143-5. doi: 10.1111/j.1748-5827.2001.tb02011.x.
A 15-year-old crossbred dog was presented with a severe cough of acute onset and an enlarged right testis. Symptomatic treatment for presumed 'kennel cough' failed to produce any improvement and at re-examination the dog had developed a swollen right forelimb. Radiographic examination suggested a diagnosis of hypertrophic pulmonary osteoarthropathy (Marie's disease) associated with pulmonary metastases from a testicular tumour. The dog was re-presented five days later with acute-onset severe vomiting and the owner elected for euthanasia. Necropsy was performed and histopathological assessment confirmed the presence of a Sertoli cell tumour in the right testis with multiple pulmonary and renal metastases. Hypertrophic pulmonary osteoarthropathy is a rare complication of metastatic canine Sertoli cell tumour. The authors know of no previously reported cases.
一只15岁的杂种犬出现急性发作的严重咳嗽和右侧睾丸肿大。针对疑似“犬窝咳”的对症治疗未见任何改善,再次检查时该犬右前肢出现肿胀。影像学检查提示诊断为与睾丸肿瘤肺转移相关的肥大性肺性骨关节病(Marie病)。五天后该犬再次就诊,出现急性发作的严重呕吐,主人选择实施安乐死。进行了尸检,组织病理学评估证实右侧睾丸存在支持细胞瘤,并伴有多处肺和肾转移。肥大性肺性骨关节病是转移性犬支持细胞瘤的一种罕见并发症。作者未了解到此前有相关病例报道。