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蝶骨血管内皮瘤:一例报告

Hemangioendothelioma of the sphenoid bone: a case report.

作者信息

Joo M, Lee G J, Koh Y C, Park Y K

机构信息

Department of Pathology, Inje University Seoul Paik Hospital, Seoul, Korea.

出版信息

J Korean Med Sci. 2001 Apr;16(2):241-4. doi: 10.3346/jkms.2001.16.2.241.

Abstract

Hemangioendothelioma is borderline or intermediate type of vascular neoplasm. Hemangioendothelioma is rare lesion that constitutes less than 0.5% of the malignant tumors of bone. We present a case of low-grade hemagioendothelioma of the skull in a 29-yr-old woman. She had pain, diplopia and exophthalmos of the left eye. Radiographic images showed a relatively well-demarcated, expansile osteolytic lesion with irregularly thickened trabeculae and calcifications in the left greater wing of sphenoid bone. Histologically, the tumor was an infiltrative vasoformative lesion. The vessels are generally well-formed with open or compressed lumina surrounded by endothelial cells showing mild atypia. It lacked frequent mitotic figures and severe atypia. Although excessive bleeding occurred during the operation, the mass was totally resected. Postoperative radiation was not necessary. She is free of disease and well 6 months postoperatively.

摘要

血管内皮瘤是一种介于良恶性之间的血管性肿瘤。血管内皮瘤是一种罕见的病变,在骨恶性肿瘤中所占比例不到0.5%。我们报告一例29岁女性的颅骨低度血管内皮瘤病例。她有疼痛、复视和左眼突出症状。影像学图像显示蝶骨大翼左侧有一个边界相对清晰、呈膨胀性的溶骨性病变,小梁不规则增厚并伴有钙化。组织学上,肿瘤是一种浸润性血管形成性病变。血管通常形态良好,管腔开放或受压,周围内皮细胞有轻度异型性。它缺乏频繁的核分裂象和严重异型性。尽管手术过程中发生了大量出血,但肿块被完全切除。术后无需放疗。术后6个月她无病且状况良好。

相似文献

1
Hemangioendothelioma of the sphenoid bone: a case report.蝶骨血管内皮瘤:一例报告
J Korean Med Sci. 2001 Apr;16(2):241-4. doi: 10.3346/jkms.2001.16.2.241.
2
Epithelioid haemangioendothelioma of the sphenoid bone.蝶骨上皮样血管内皮瘤
J Clin Neurosci. 2001 May;8 Suppl 1:63-6. doi: 10.1054/jocn.2001.0880.
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Hemangioendothelioma of bone with pulmonary metastases: a 25-year course: report of a case.骨血管内皮瘤伴肺转移:25年病程:病例报告
Cancer. 1979 May;43(5):1917-23. doi: 10.1002/1097-0142(197905)43:5<1917::aid-cncr2820430550>3.0.co;2-6.
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Malignant hemangioendothelioma of bone.骨恶性血管内皮瘤
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