高剂量率近距离放射治疗在非恶性支气管阻塞中的成功应用。
Successful use of high dose rate brachytherapy for non-malignant bronchial obstruction.
作者信息
Kramer M R, Katz A, Yarmolovsky A, Schifter D, Fenig E
机构信息
Pulmonary Institute, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel.
出版信息
Thorax. 2001 May;56(5):415-6. doi: 10.1136/thorax.56.5.415.
High dose rate (HDR) endobronchial brachytherapy is a palliative treatment for symptomatic airway obstruction by malignant tumours. We report a novel use of HDR brachytherapy for treating non-malignant bronchial obstruction. The patient had a metal stent placed in a reconstructed airway after a bronchial tear to ensure patency. Granulation tissue formation in and around the stent caused symptomatic occlusion of the airway, necessitating multiple laser applications. A single treatment of HDR brachytherapy (1000 cGy) was delivered following laser therapy. The patient remains well 15 months after treatment with no evidence of recurrent granulation tissue formation on bronchoscopy. HDR brachytherapy is an effective treatment for non-malignant airway obstruction.
高剂量率（HDR）支气管内近距离放射治疗是一种针对恶性肿瘤所致有症状气道阻塞的姑息治疗方法。我们报告了HDR近距离放射治疗在治疗非恶性支气管阻塞方面的一种新用途。该患者在支气管撕裂后于重建气道内放置了金属支架以确保通畅。支架内及周围的肉芽组织形成导致气道出现有症状的阻塞，需要多次进行激光治疗。在激光治疗后进行了单次HDR近距离放射治疗（1000 cGy）。治疗后15个月患者情况良好，支气管镜检查未发现肉芽组织复发形成的迹象。HDR近距离放射治疗是治疗非恶性气道阻塞的有效方法。
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