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嗜肺巴斯德杆菌的生存能力与传播性

Survival and transmissibility of Pasteurella pneumotropica.

作者信息

Scharmann W, Heller A

机构信息

Bundesinstitut für Gesundheitlichen Verbraucherschutz und Veterinärmedizin, Fachgebiet Versuchstierkunde, Berlin.

出版信息

Lab Anim. 2001 Apr;35(2):163-6. doi: 10.1258/0023677011911543.

Abstract

Survival has been determined for Pasteurella pneumotropica on various surfaces found in an animal room at 23+/-1 degrees C and 50+/-10% relative humidity. Longest survival (120 min) was found on mouse hair, shortest (< 30 min) on laboratory coat fabric. Transmission experiments were performed using sentinel animals in order to evaluate the efficiency of their use for the detection of P. pneumotropica in quarantined mice. In sentinels exposed to infected mice by close contact, P. pneumotropica was detected by culture 2 weeks post-exposure and seroconversion 3 weeks after contact. Transfer of soiled bedding from Pasteurella-infected mice did not infect sentinels within a period of 12 weeks as tested by cultivation or serum antibodies.

摘要

已测定嗜肺巴斯德杆菌在动物房内23±1℃、相对湿度50±10%条件下不同表面上的存活情况。在小鼠毛发上存活时间最长(120分钟),在实验室白大衣织物上存活时间最短(<30分钟)。为评估哨兵动物用于检测隔离小鼠中嗜肺巴斯德杆菌的效率,进行了传播实验。在通过密切接触暴露于感染小鼠的哨兵动物中,暴露后2周通过培养检测到嗜肺巴斯德杆菌,接触后3周出现血清转化。如通过培养或血清抗体检测,在12周的时间内,来自感染巴斯德杆菌小鼠的脏垫料转移并未感染哨兵动物。

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