Baschat A A, Harman C R
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, Baltimore 21201-1703, USA.
Curr Opin Obstet Gynecol. 2001 Apr;13(2):161-8. doi: 10.1097/00001703-200104000-00011.
Babies who are small due to intrauterine growth restriction are at higher risk for poor perinatal and long-term outcome than those who are appropriately grown. Through multiple antenatal testing modalities a sequence of deteriorating fetal status can be documented in such cases. The nature of this compromise is best reflected by the combination of fetal biometry, biophysical profile scoring and arterial and venous Doppler. This combination accurately defines fetal states and therefore risk of stillbirth or poor transition to extrauterine life. In the preterm neonate, fetal factors, gestational age and neonatal course interact significantly to impact on short- and long-term outcomes. The potential for iatrogenic prematurity is great and ongoing appraisal of peripartum management is critical. An integrated management protocol accounting for these factors is examined in this review.
因宫内生长受限而体重较轻的婴儿,与生长正常的婴儿相比,围产期及长期预后不良的风险更高。在这些病例中,通过多种产前检查方式,可以记录到胎儿状况逐渐恶化的过程。胎儿生物测量、生物物理评分以及动静脉多普勒检查相结合,最能反映这种损害的性质。这种组合能够准确界定胎儿状态,进而确定死产风险或宫外生活过渡不良的风险。对于早产儿,胎儿因素、胎龄和新生儿病程之间存在显著相互作用,会影响短期和长期预后。医源性早产的可能性很大,因此对围产期管理进行持续评估至关重要。本综述探讨了一个综合考虑这些因素的管理方案。