Babincová M, Susteková E, Machová E
Department of Biophysics and Chemical Physics, Comenius University, Bratislava, Slovakia.
Gen Physiol Biophys. 2000 Sep;19(3):323-7.
Laminarin, a water-soluble polysaccharide is known to induce aggregation and fusion of liposomes. Using laminarin specific lysing enzymes for multi-lamellar liposomes their aggregation was found to be fully reversible, in contrast to small unilamellar liposomes for which irreversible fusion is the main process. Moreover, our results indicate that these processes are probably mediated by the formation of polysaccharide cross-bridges between adjacent liposomes.
海带多糖是一种水溶性多糖，已知它能诱导脂质体聚集和融合。使用针对多层脂质体的海带多糖特异性裂解酶时，发现其聚集是完全可逆的，这与小单层脂质体不同，对于小单层脂质体，不可逆融合是主要过程。此外，我们的结果表明，这些过程可能是由相邻脂质体之间多糖交联桥的形成介导的。
