[委内瑞拉脑炎病毒疫苗株对实验性肿瘤的联合治疗]
[Combined therapy of experimental tumors with the vaccinal strain of Venezulean encephalomyelitis virus].
作者信息
Urazova L N, Gromova A I
机构信息
Research Institute of Oncology, Research Center, Russian Academy of Medical Sciences, Siberian Branch, Tomsk.
出版信息
Vopr Onkol. 2001;47(1):78-80.
PMID:11317543
Abstract
The potential of therapy with vaccinal strain of Venezuelan encephalomyelitis virus (VEL) in conjunction with cytostatics (cyclophosphamide) or immunomodulators (T-activin) has been studied. It was found that VEL in conjunction with cyclophosphamide inhibited the antitumor action of the drugs while T-activin potentiated the same effects of the virus and its oncolysate.
摘要
对委内瑞拉马脑炎病毒（VEL）疫苗株与细胞抑制剂（环磷酰胺）或免疫调节剂（T-激活素）联合进行治疗的潜力进行了研究。结果发现，VEL与环磷酰胺联合使用会抑制药物的抗肿瘤作用，而T-激活素则增强了病毒及其肿瘤溶解产物的相同作用。
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