Identification of phosphorodiamidic acid mustard as a human metabolite of cyclop hosphamide.
作者信息
Fenselau C, Kan M N, Billets S, Colvin M
出版信息
Cancer Res. 1975 Jun;35(6):1453-7.
PMID:1131817
Abstract
An active metabolite of cyclophosphamide, N,N-bis(2-chloroethyl)phosphorodiamidic acid, has been confirmed as a circulating and excreted metabolite in patients receiving the drug in therapy, by selected ion monitoring on a gas chromatograph mass spectrometer.
摘要
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