Syring R S, Otto C M, Drobatz K J
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104, USA.
J Am Vet Med Assoc. 2001 Apr 1;218(7):1124-9. doi: 10.2460/javma.2001.218.1124.
To determine whether hyperglycemia is associated with head trauma in dogs and cats and whether the degree of hyperglycemia corresponds to severity of neurologic injury or outcome.
Retrospective study.
52 dogs and 70 cats with head trauma and 122 age- and species-matched control dogs and cats.
Severity of head trauma was classified as mild, moderate, or severe. Blood glucose concentrations recorded within 1 hour after admission were compared between case and control animals and among groups when case animals were grouped on the basis of severity of head trauma or outcome.
Blood glucose concentration was significantly associated with severity of head trauma in dogs and cats and was significantly higher in dogs and cats with head trauma than in the control animals. However, blood glucose concentration was not associated with outcome.
Results suggest that dogs and cats with head trauma may have hyperglycemia and that degree of hyperglycemia was associated with severity of head trauma. However, degree of hyperglycemia was not associated with outcome for dogs and cats with head trauma. Because hyperglycemia can potentiate neurologic injury, iatrogenic hyperglycemia should be avoided in patients with head trauma.
确定高血糖是否与犬猫头部创伤相关，以及高血糖程度是否与神经损伤的严重程度或预后相关。
回顾性研究。
52只患有头部创伤的犬和70只患有头部创伤的猫，以及122只年龄和物种匹配的对照犬和猫。
将头部创伤的严重程度分为轻度、中度或重度。比较病例动物和对照动物入院后1小时内记录的血糖浓度，并在根据头部创伤严重程度或预后对病例动物进行分组时比较各组之间的血糖浓度。
血糖浓度与犬猫头部创伤的严重程度显著相关，患有头部创伤的犬猫的血糖浓度显著高于对照动物。然而，血糖浓度与预后无关。
结果表明，患有头部创伤的犬猫可能存在高血糖，且高血糖程度与头部创伤的严重程度相关。然而，高血糖程度与患有头部创伤的犬猫的预后无关。由于高血糖可加重神经损伤，因此应避免头部创伤患者出现医源性高血糖。
