Phaf H R, Geurts H, Eling P A
Psychonomics Department, University of Amsterdam, The Netherlands.
J Clin Exp Neuropsychol. 2000 Dec;22(6):817-29. doi: 10.1076/jcen.22.6.817.956.
Korsakoff patients are generally agreed to be impaired in conscious recollection, but whether their implicit memory performance is also affected is less certain. A deficit in novelty dependent encoding (i.e., elaboration learning) could account for both types of impairments and predicts a reduced implicit word frequency effect in the patients. This effect was examined with word stem completion in nineteen Korsakoff patients and nineteen healthy controls. The word frequency effect was larger in controls than in patients in absolute terms, but not reliably so. It is concluded that elaboration learning may be spared to some degree in Korsakoff amnesia, but, in line with the original reasoning by Korsakoff (1889/1996), it may only be engaged by the patients when they are continuously prompted to do so.
一般认为柯萨科夫综合征患者的意识性回忆受损，但他们的内隐记忆表现是否也受影响则不太确定。新奇依赖编码（即精细化学习）缺陷可以解释这两种类型的损伤，并预测患者内隐词频效应降低。通过词干补全任务对19名柯萨科夫综合征患者和19名健康对照者进行了此项效应检测。绝对而言，对照组的词频效应大于患者组，但差异并不显著。研究得出结论，在柯萨科夫遗忘症中，精细化学习可能在一定程度上未受影响，但与柯萨科夫（1889/1996）最初的推理一致，只有在不断提示的情况下患者才会进行精细化学习。
