Matsuno T, Tsushima M, Maoka T
Kyoto Pharmaceutical University, Misasagi, Yamashina, Kyoto 607-8412, Japan.
J Nat Prod. 2001 Apr;64(4):507-10. doi: 10.1021/np0004294.
The absolute configuration of salmoxanthin (5,6-epoxy-5,6-dihydro-beta,epsilon-carotene-3,3',6'-triol) (1) first isolated from the salmon Oncorhynchus keta was determined to be 3S, 5R, 6S, 3'S, 6'R. Furthermore, two minor carotenoids, deepoxysalmoxanthin (2) and 7,8-didehydrodeepoxysalmoxanthin (3), were isolated, and their structures were determined to be (3R,3'S,6'R)-beta,epsilon-carotene-3,3',6'-triol and (3R,3'S,6'R)-7,8-didehydro-beta,epsilon-carotene-3,3',6'-triol by (1)H NMR and CD spectroscopy.
首次从鲑鱼大麻哈鱼中分离得到的虾青素（5,6-环氧-5,6-二氢-β,ε-胡萝卜素-3,3',6'-三醇）（1）的绝对构型被确定为3S, 5R, 6S, 3'S, 6'R。此外，还分离出了两种次要类胡萝卜素，即脱环氧虾青素（2）和7,8-二脱氢脱环氧虾青素（3），通过¹H NMR和CD光谱确定它们的结构分别为(3R,3'S,6'R)-β,ε-胡萝卜素-3,3',6'-三醇和(3R,3'S,6'R)-7,8-二脱氢-β,ε-胡萝卜素-3,3',6'-三醇。
