褪黑素或阿尔茨舒尔松果体提取物对猕猴（食蟹猴）雌激素和孕酮分泌的影响

Estrogen and progesterone secretion in monkeys (Macaca fascicularis) following melatonin or Altschule's pineal extrac.

作者信息

Fiske V M, MacDonald G J, Bigelow L L, Altschule M D

出版信息

Fertil Steril. 1975 Jun;26(6):613-6. doi: 10.1016/s0015-0282(16)41181-7.

Abstract

Large doses (30MG) of melatonin given weekly to crab-eating monkeys throughout five menstrual cycles did not change the pattern of estrogen and progesterone secretion during the period of injection or in the two succeeding cycles. Altschule's pineal extract, unlike melatonin, had no effect on estrogen or progesterone secretion during the period of injection or in the two succeeding cycles, when it was given daily between days 7 and 17 of the menstrual cycle.

摘要

在五个月经周期内，每周给食蟹猴注射大剂量（30毫克）褪黑素，在注射期间以及随后的两个周期内，雌激素和孕酮的分泌模式均未改变。与褪黑素不同，阿尔茨舒尔松果体提取物在月经周期第7至17天每天给药时，在注射期间以及随后的两个周期内，对雌激素或孕酮的分泌均无影响。