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免疫功能正常的年轻成年人感染幽门螺杆菌属弯曲螺菌血症

Helicobacter sp. flexispira bacteremia in an immunocompetent young adult.

作者信息

Iten A, Graf S, Egger M, Täuber M, Graf J

机构信息

University Hospital Insel, University of Berne, Friedbühlstr. 51, CH-3010 Berne, Switzerland.

出版信息

J Clin Microbiol. 2001 May;39(5):1716-20. doi: 10.1128/JCM.39.5.1716-1720.2001.

Abstract

A young immunocompetent patient was admitted for a febrile illness with malaise, arthralgias, painful leg swelling, and polyserositis. Shortly prior to becoming ill, the patient had traveled to the Northern African desert. The symptoms disappeared during treatment with antibiotics (doxycycline and ceftriaxone) but recurred twice after stopping therapy. A motile gram-negative fusiform rod was isolated from a blood culture taken on the first admission. Analysis of the 16S rRNA gene of the blood culture isolate revealed close similarity with Helicobacter sp. flexispira taxon 8 (99.9% identity), a species that was previously reported as "Flexispira rappini." This is the first reported case of a recurrent Helicobacter sp. flexispira bacteremia in an adult, immunocompetent patient.

摘要

一名年轻的免疫功能正常患者因发热性疾病入院,伴有全身不适、关节痛、腿部疼痛性肿胀和多浆膜炎。在发病前不久,该患者前往了北非沙漠。症状在使用抗生素(强力霉素和头孢曲松)治疗期间消失,但在停止治疗后复发了两次。从首次入院时采集的血培养物中分离出一种运动性革兰氏阴性梭形杆菌。对血培养分离株的16S rRNA基因分析显示,它与幽门螺杆菌属弯曲螺菌分类群8(相似度99.9%)密切相似,该物种以前被报告为“拉氏弯曲螺菌”。这是首次报道的成年免疫功能正常患者复发性幽门螺杆菌属弯曲螺菌菌血症病例。

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