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粘孢子虫属,免疫抑制患者中的另一种机会性寄生虫?

Myxobolus sp., another opportunistic parasite in immunosuppressed patients?

作者信息

Moncada L I, López M C, Murcia M I, Nicholls S, León F, Guío O L, Corredor A

机构信息

Departamento de Salud Pública y Tropical, Facultad de Medicina Universidad Nacional de Colombia, Bogotá, Colombia.

出版信息

J Clin Microbiol. 2001 May;39(5):1938-40. doi: 10.1128/JCM.39.5.1938-1940.2001.

DOI:10.1128/JCM.39.5.1938-1940.2001
PMID:11326017
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC88052/
Abstract

During a study of intestinal parasitic infections in human immunodeficiency virus-positive patients, a parasite belonging to the phylum Myxozoa, recently described from human samples, was identified in one sample. When this parasite was stained by the modified Ziehl-Neelsen staining method, the features of the spores were identified: they were pyriform in shape, had thick walls, and had one suture and two polar capsules, with each one having four or five coils. The suture and two polar capsules were observed with the chromotrope-modified stain. The number of stools passed was more than 30 per day, but oocysts of Isospora belli were also found. Upon reexamination of some formalin- or merthiolate-iodine-formaldehyde-preserved samples an identical parasite was found in another sample from a patient presenting with diarrhea. Strongyloides stercoralis larvae and eggs of Hymenolepis nana and Ascaris lumbricoides were also found in this sample. Given that both patients were also infected with other pathogens that cause diarrhea, the possible pathogenic role of this parasite could not be established. The probable route of infection also could not be established.

摘要

在一项针对人类免疫缺陷病毒阳性患者肠道寄生虫感染的研究中,在一份样本中发现了一种属于粘孢子虫门的寄生虫,该寄生虫最近才从人类样本中被描述出来。当用改良的齐尔-尼尔森染色法对这种寄生虫进行染色时,孢子的特征得以确定:它们呈梨形,壁厚,有一条缝线和两个极囊,每个极囊有四到五个螺旋。用变色染料改良染色法可观察到缝线和两个极囊。患者每天排便次数超过30次,同时还发现了贝氏等孢球虫的卵囊。在重新检查一些用福尔马林或硫柳汞-碘-甲醛保存的样本时,在另一名腹泻患者的样本中发现了相同的寄生虫。在该样本中还发现了粪类圆线虫幼虫以及微小膜壳绦虫和蛔虫的卵。鉴于两名患者均感染了其他导致腹泻的病原体,这种寄生虫可能的致病作用无法确定。感染的可能途径也无法确定。

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