Nikkari S, McLaughlin I J, Bi W, Dodge D E, Relman D A
Department of Microbiology and Immunology and Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
J Clin Microbiol. 2001 May;39(5):1956-9. doi: 10.1128/JCM.39.5.1956-1959.2001.
Real-time PCR methods with primers and a probe targeting conserved regions of the bacterial 16S ribosomal DNA (rDNA) revealed a larger amount of rDNA in blood specimens from healthy individuals than in matched reagent controls. However, the origins and identities of these blood-associated bacterial rDNA sequences remain obscure.
使用针对细菌16S核糖体DNA(rDNA)保守区域的引物和探针的实时PCR方法显示,健康个体血液样本中的rDNA量比匹配的试剂对照中的rDNA量更多。然而,这些与血液相关的细菌rDNA序列的来源和身份仍然不明。