Salvati M, Cervoni L
Department of Neurosurgery, Mediterranean Neurological Neuromed Institute IRCCS, Pozzilli, Isernia, Italy.
J Neurosurg Sci. 2000 Dec;44(4):230-2; discussion 232-3.
Medulloblastoma in late adults (older than 65 years) is an exceptional occurrence; in fact only 8 cases are reported with complete clinical notes in the literature.
The authors describe a case of medulloblastoma occurring in a 68-year-old man and analyzed cases reported in the literature.
The overall average age of the patients was 72.8 years (range 67-88 years), and the male prevalence of this tumour (70% of cases) seems to be unrelated to age. There is a lateral predominance in late adults (77.7% of cases). Seven patients underwent operation and subsequently these patients underwent a course of radiation therapy. Only two patient was treated with postoperative chemotherapy. Median survival for seven patients treated was 43.2 months (range 23-96 months).
It is interesting to note that: 1) histological analysis revealed a classic type medulloblastoma (88.8% of cases) similar to the children: 2) site of the tumor is lateral similar to the adults (77.7% of cases).
老年晚期（65岁以上）髓母细胞瘤极为罕见；事实上，文献中仅报道了8例有完整临床记录的病例。
作者描述了1例发生在68岁男性身上的髓母细胞瘤病例，并分析了文献中报道的病例。
患者的总体平均年龄为72.8岁（范围67 - 88岁），该肿瘤的男性患病率（70%的病例）似乎与年龄无关。老年晚期患者中肿瘤多位于侧方（77.7%的病例）。7例患者接受了手术，随后这些患者接受了一个疗程的放射治疗。仅2例患者接受了术后化疗。接受治疗的7例患者的中位生存期为43.2个月（范围23 - 96个月）。
值得注意的是：1）组织学分析显示，88.8%的病例为与儿童相似的经典型髓母细胞瘤；2）肿瘤部位与成人相似，位于侧方（77.7%的病例）。
