Inagaki T, Hagino K, Matsumura N, Koh M, Nishikawa T, Suzuki A, Hirano A, Shinka T
Department of Urology, Wakayama Medical College.
Hinyokika Kiyo. 2001 Mar;47(3):183-6.
We report a case of collecting duct carcinoma (Bellini duct carcinoma) producing carcinoembryonic antigen (CEA). A 61-year-old man visited our hospital because of a left renal mass detected by ultrasonography in an other hospital. Computed tomography showed a low density tumor measuring about 3 cm in the left kidney. Angiography demonstrated a hypovascular tumor. The serum level of CEA was increased to 20 ng/ml. (normal < 7 ng/ml). Left radical nephrectomy was performed. Histological examination revealed collecting duct carcinoma with papillary growth (T1aN1M0). Cancer cells showed a positive immunohistochemical staining for CEA. Under a diagnosis of CEA-producing collecting duct carcinoma of the left kidney, the patient underwent systemic chemotherapy (M-VAC). The serum level of CEA decreased to the normal level after the nephrectomy, but six months postoperatively, metastatic bone tumor at the left pelvic bone was revealed on the plain film and at the same time, the CEA level was increased again.
我们报告一例产生癌胚抗原(CEA)的集合管癌(贝氏管癌)。一名61岁男性因在其他医院超声检查发现左肾肿物而来我院就诊。计算机断层扫描显示左肾有一个直径约3 cm的低密度肿瘤。血管造影显示为少血管肿瘤。血清CEA水平升高至20 ng/ml(正常<7 ng/ml)。行左根治性肾切除术。组织学检查显示为具有乳头状生长的集合管癌(T1aN1M0)。癌细胞CEA免疫组化染色呈阳性。在诊断为左肾产生CEA的集合管癌后,患者接受了全身化疗(M-VAC)。肾切除术后血清CEA水平降至正常,但术后6个月,X线平片显示左骨盆骨出现转移性骨肿瘤,同时CEA水平再次升高。