Armstrong D N, Ambroze W L, Schertzer M E, Orangio G R
Georgia Colon and Rectal Surgical Clinic, Atlanta 30342, USA.
Dis Colon Rectum. 2001 Apr;44(4):558-64. doi: 10.1007/BF02234329.
Management of posthemorrhoidectomy pain remains a very unsatisfactory clinical dilemma. Compared with electrocautery and laser, the Harmonic Scalpel causes minimal lateral thermal injury during tissue dissection.
The aim of the study was to establish whether decreased lateral thermal injury translated into diminished posthemorrhoidectomy pain.
A prospective randomized trial comparing Harmonic Scalpel hemorrhoidectomy and electrocautery was undertaken. Fifty consecutive patients were randomized into two groups: Harmonic Scalpels and electrocautery hemorrhoidectomy. The indications included Grade III internal hemorrhoids with external components or Grade IV disease. Patients with additional anorectal pathology (fissure or fistula) were excluded, as were patients with neurologic deficits, chronic pain syndrome, and those already taking narcotic analgesics. Pain was assessed using a visual analog scale preoperatively and on postoperative Days 1, 2, 7, 14, and 28. Twenty-four-hour narcotic usage (Hydrocodone, 10 mg) was recorded on postoperative Days 1, 2, 7, 14, and 28. A three-quadrant modified Ferguson hemorrhoidectomy was performed with each patient in the prone jackknife position.
Pain in the Harmonic Scalpel hemorrhoidectomy group was significantly less than in electrocautery patients on each postoperative day studied. Analgesic requirements were also significantly less in the Harmonic Scalpel group on Days 1, 2, 7, and 14. There was no correlation between postoperative pain and grade of hemorrhoid, status of the surgical incision (open vs. closed), or any other study variable. Fifty-five percent of Harmonic Scalpel patients returned to work within one week of surgery, compared with 23 percent of electrocautery patients.
The study demonstrates significantly reduced postoperative pain after Harmonic Scalpel hemorrhoidectomy compared with electrocautery controls. The diminished postoperative pain in the Harmonic Scalpel group likely results from the avoidance of lateral thermal injury.
痔切除术后疼痛的管理仍然是一个非常不尽人意的临床难题。与电灼术和激光相比,超声刀在组织切割过程中造成的侧向热损伤最小。
本研究的目的是确定侧向热损伤的减少是否转化为痔切除术后疼痛的减轻。
进行了一项比较超声刀痔切除术和电灼术的前瞻性随机试验。连续50例患者被随机分为两组:超声刀组和电灼痔切除术组。适应症包括伴有外痔成分的III度内痔或IV度疾病。排除有其他肛肠病变(肛裂或肛瘘)的患者,以及有神经功能缺损、慢性疼痛综合征的患者和那些已经在服用麻醉性镇痛药的患者。术前以及术后第1、2、7、14和28天使用视觉模拟量表评估疼痛。记录术后第1、2、7、14和28天的24小时麻醉剂使用量(氢可酮,10毫克)。每位患者均在俯卧折刀位进行三象限改良弗格森痔切除术。
在研究的每个术后日中,超声刀痔切除术组的疼痛明显低于电灼术患者。在术后第1、2、7和14天,超声刀组的镇痛需求也明显较少。术后疼痛与痔疮分级、手术切口状态(开放与闭合)或任何其他研究变量之间均无相关性。55%的超声刀组患者在术后一周内恢复工作,而电灼术患者的这一比例为23%。
该研究表明,与电灼术对照组相比,超声刀痔切除术后的术后疼痛明显减轻。超声刀组术后疼痛减轻可能是由于避免了侧向热损伤。