Kønig K B, Eiken P A, Schwarz P
Medicinsk afdeling F, Amtssygehuset i Gentofte.
Ugeskr Laeger. 2001 Apr 9;163(15):2129-33.
SERM describes a category of drugs that exert their influence on estrogen-sensitive tissue and are known especially in the treatment of estrogen receptor-positive breast cancer. The development and clinical trials of new SERM in recent years seem to establish more fields of diseases, where treatment with SERM may be indicated.
选择性雌激素受体调节剂(SERM)是一类对雌激素敏感组织有影响的药物,尤其在雌激素受体阳性乳腺癌的治疗中广为人知。近年来新型SERM的研发及临床试验似乎确立了更多可能适用SERM治疗的疾病领域。