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“甘草性高血压”也由甘草茶引起。

['Licorice hypertension' also caused by licorice tea].

作者信息

Brouwers A J, van der Meulen J

机构信息

Albert Schweitzer Ziekenhuis, locatie Dordwijk, afd. Interne Geneeskunde, Postbus 306, 3300 AH Dordrecht.

出版信息

Ned Tijdschr Geneeskd. 2001 Apr 14;145(15):744-7.

Abstract

A 41-year-old woman, who presented with (apparent) essential hypertension, was treated with atenolol and candesartan. This treatment, however, was unsuccessful. After the addition of hydrochlorothiazide (HCT) to the combination, she developed hypokalaemia with muscle cramps and weakness. This hypokalaemia persisted for more than 4 weeks after discontinuation of HCT and starting potassium suppletion. As a result of polyuria (> 4000 ml/day) found in a 24-hour urine collection, it was discovered that the patient drank at least 3 litres of liquorice tea a day. She had denied eating liquorice sweets, a well-known cause of hypertension in the Netherlands, but no one had thought of asking her if she drank liquorice tea. Blood pressure and serum potassium normalized about 2 months after she stopped drinking liquorice tea, and medication was withdrawn. In a patient presenting with hypertension and hypokalaemia, who denies eating liquorice sweets, one should consider the consumption of other products containing liquorice such as liquorice tea. In the Netherlands liquorice tea is increasingly popular and has recently become available on a large scale. Therefore more cases such as the one described may be expected in coming years.

摘要

一名41岁的女性,表现为(明显的)原发性高血压,接受了阿替洛尔和坎地沙坦治疗。然而,这种治疗并不成功。在联合用药中加入氢氯噻嗪(HCT)后,她出现了低钾血症,伴有肌肉痉挛和无力。停用HCT并开始补钾后,这种低钾血症持续了4周以上。通过24小时尿液收集发现患者每天尿量增多(>4000毫升/天),结果发现该患者每天至少饮用3升甘草茶。她否认食用甘草糖,而在荷兰甘草糖是高血压的一个众所周知的病因,但没人想到询问她是否饮用甘草茶。在她停止饮用甘草茶约2个月后,血压和血钾恢复正常,药物停用。对于一名患有高血压和低钾血症且否认食用甘草糖的患者,应考虑其是否食用了其他含甘草的产品,如甘草茶。在荷兰,甘草茶越来越受欢迎,最近已大量上市。因此,预计未来几年会出现更多此类病例。

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