Powell J L, Connor G P, Henderson G S
Department of Obstetrics and Gynecology, New Hanover Regional Medical Center, Wilmington, NC, USA.
South Med J. 2001 Apr;94(4):450-3.
A case of androgen-secreting borderline endometrioid tumor arising in endometriosis of the rectovaginal septum is presented. It occurred 10 years after total abdominal hysterectomy and bilateral salpingo-oophorectomy for extensive endometriosis of the fallopian tubes and ovaries, adenomyosis, and leiomyomas of the uterus. We believe 7 years of unopposed continuous oral estrogen replacement therapy contributed to the malignant transformation of the endometriosis.
本文报告一例发生于直肠阴道隔子宫内膜异位症的分泌雄激素的交界性子宫内膜样肿瘤。该肿瘤发生于因广泛的输卵管和卵巢子宫内膜异位症、子宫腺肌病及子宫肌瘤行全腹子宫切除术和双侧输卵管卵巢切除术10年后。我们认为7年无对抗的持续口服雌激素替代治疗促成了子宫内膜异位症的恶变。