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[一名基底动脉动脉瘤患者的反复中风]

[Repeated strokes in a patient with a basilar artery aneurysm].

作者信息

Arenas-Cabrera C, Martínez-Fernández E, Gil-Peralta A, Sánchez-Huelva A, Cabrera-Pérez R, Chinchón-Lara I

机构信息

Servicio de Neurología; Hospital Universitario Virgen del Rocío, Sevilla, 41013, España.

出版信息

Rev Neurol. 2001;32(4):335-8.

Abstract

INTRODUCTION

The estimated prevalence of basilar dolichoectasia in the healthy general population is 50 per 100,000 inhabitants. The treatment of symptomatic cases is controversial. Strokes caused by it may be due to thrombosis of the perforating arteries, arterio-arterial emboli or a compressive mechanism.

CLINICAL CASE

We present the case of a 68 year old woman with repeated stokes in which the vertebrobasilar territory was involved. On neuroimaging there was basilar dolichoectasia associated with aneurismal dilatation of both internal carotid arteries. The patient died of massive subarachnoid hemorrhage after starting heparin treatment. At necropsy the aneurysmic dilatation was confirmed together with signs of arteriosclerosis of the arteries of the circle of Willis.

CONCLUSIONS

Since subarachnoid hemorrhage secondary to rupture of a dolichoectasia is exceptional, some authors support the use of permanent anticoagulation rather than platelet antiaggregation in patients with conditions due to ischemia, in which dilatation is limited to the basilar artery. However, this is not suitable for cases with associated fusiform aneuryms, or cases such as ours in which the dolichoectasia extends beyond the basilar artery, to become generalized throughout all the arteries of the circle of Willis.

摘要

引言

健康普通人群中基底动脉延长扩张症的估计患病率为每10万居民中有50例。有症状病例的治疗存在争议。由其引起的中风可能是由于穿支动脉血栓形成、动脉-动脉栓塞或压迫机制。

临床病例

我们报告一例68岁女性反复中风累及椎基底动脉区域的病例。神经影像学检查显示基底动脉延长扩张并伴有双侧颈内动脉动脉瘤样扩张。患者在开始肝素治疗后死于大量蛛网膜下腔出血。尸检证实存在动脉瘤样扩张以及 Willis 环动脉的动脉硬化迹象。

结论

由于基底动脉延长扩张破裂继发蛛网膜下腔出血的情况较为罕见,一些作者支持对因缺血导致病情、且扩张仅限于基底动脉的患者使用长期抗凝治疗而非血小板抗聚集治疗。然而,这不适用于伴有梭形动脉瘤的病例,或像我们这样基底动脉延长扩张超出基底动脉范围、累及 Willis 环所有动脉的病例。

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