Kynurenic acid does not protect against nicotine-induced seizures in mice.
作者信息
Kiś J, Czuczwar M, Zielińska E, Bojar I, Czuczwar S J, Turski W A
机构信息
Department of Pharmacology and Toxicology, Medical University, Lublin, Poland.
出版信息
Pol J Pharmacol. 2000 Nov-Dec;52(6):477-80.
PMID:11334243
Abstract
Kynurenic acid, an antagonist of glutamatergic ionotropic receptors and alpha7 nicotinic cholinergic receptors failed to affect nicotine-induced convulsions in mice which may indicate that alpha7 nicotinic receptor-mediated events play no role in seizure activity produced by nicotine.
摘要
Zotero 插件