Wagner A
University of New Mexico, Dept of Biology, 167A Castetter Hall, Albuquerque, NM 817131-1091, USA.
Trends Genet. 2001 May;17(5):237-9. doi: 10.1016/s0168-9525(01)02243-0.
Gene and genome duplications are commonly regarded as being of major evolutionary significance. But how often does gene duplication occur? And, once duplicated, what are the fates of duplicated genes? How do they contribute to evolution? In a recent article, Lynch and Conery analyze divergence between duplicate genes from six eukaryotic genomes. They estimate the rate of gene duplication, the rate of gene loss after duplication and the strength of selection experienced by duplicate genes. They conclude that although the rate of gene duplications is high, so is the rate of gene loss, and they argue that gene duplications could be a major factor in speciation.
基因和基因组复制通常被认为具有重大的进化意义。但是基因复制多久发生一次呢？而且，一旦发生复制，复制基因的命运如何？它们如何促进进化？在最近的一篇文章中，林奇和科纳里分析了来自六个真核生物基因组的复制基因之间的差异。他们估计了基因复制的速率、复制后基因丢失的速率以及复制基因所经历的选择强度。他们得出结论，尽管基因复制的速率很高，但基因丢失的速率也很高，并且他们认为基因复制可能是物种形成的一个主要因素。
