Vázquez Blanco M, Grosso O, Bellido C A, Iavícoli O R, Berensztein C S, Ruda Vega H, Lerman J
Division of Cardiology, Hospital de Clínicas José de San Martín, University of Buenos Aires, Argentina.
Am J Hypertens. 2001 Apr;14(4 Pt 1):390-2. doi: 10.1016/s0895-7061(00)01250-4.
Chronic hypertension induces changes in the structure of the left ventricle, atrium, and aortic root. However, the effects of transient hypertension are unclear. Pregnancy-induced hypertension (PIH) offers a natural and spontaneous model of this condition. Using M-mode echocardiography, we studied 95 consecutive patients with PIH, who were compared with 83 normal pregnant women (NPW). We evaluated diastolic diameter (DD), systolic diameter (SD), septal thickness (ST), posterior wall thickness (PWT), shortening fraction (SF), relative wall thickness (RWT), left ventricular mass index (LVMI), left atrial dimension (LAD), and aortic root dimension (ARD). Patients with PIH had higher ST (9.98 +/- 1.47 mm v 8.96 +/- 1.43 mm, P < .000), PWT (9.28 +/- 1.48 mm v 8.55 +/- 1.35 mm, P < .000), LVMI (107.65 +/- 27.87 g/m2 v 92.38 +/- 17.99 g/m2, P < .000), and RWT (0.406 +/- 0.06 v 0.377 +/- 0.06 mm, P < .002). There were no significant differences in DD, SD, SF, LAD, and ARD. In conclusion, PIH increases the LVMI due to an increase in the ST and PWT. The dimensions of the left ventricle, left atrium, and aortic root do not change.
慢性高血压会导致左心室、心房和主动脉根部结构发生改变。然而,短暂性高血压的影响尚不清楚。妊娠高血压综合征(PIH)为此提供了一个自然且自发的模型。我们使用M型超声心动图对95例连续的PIH患者进行了研究,并将其与83例正常孕妇(NPW)进行比较。我们评估了舒张期直径(DD)、收缩期直径(SD)、室间隔厚度(ST)、后壁厚度(PWT)、缩短分数(SF)、相对壁厚度(RWT)、左心室质量指数(LVMI)、左心房内径(LAD)和主动脉根部内径(ARD)。PIH患者的ST(9.98±1.47mm对8.96±1.43mm,P<.000)、PWT(9.28±1.48mm对8.55±1.35mm,P<.000)、LVMI(107.65±27.87g/m²对92.38±17.99g/m²,P<.000)和RWT(0.406±0.06对0.377±0.06mm,P<.002)更高。DD、SD、SF、LAD和ARD无显著差异。总之,PIH由于ST和PWT增加而使LVMI升高。左心室、左心房和主动脉根部的内径没有变化。