口服制剂对肺炎链球菌儿科分离株的活性。
Activity of oral agents against pediatric isolates of Streptococcus pneumoniae.
作者信息
Black J, Moland E S, Chartrand S A, Thomson K S
机构信息
Center for Research in Anti-Infectives and Biotechnology, Department of Medical Microbiology and Immunology, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE 68178, USA.
出版信息
Diagn Microbiol Infect Dis. 2001 Mar;39(3):195-7. doi: 10.1016/s0732-8893(01)00209-7.
An in vitro study of the activity of 10 oral agents against 153 pediatric isolates of Streptococcus pneumoniae identified moxifloxacin and levofloxacin as the most active agents regardless of penicillin or macrolide susceptibility. Moxifloxacin inhibited all strains at 0.25 microg/ml and was 8- to 16-fold more potent than levofloxacin.
一项针对10种口服药物对153株儿童肺炎链球菌分离株活性的体外研究表明，无论青霉素或大环内酯类药物敏感性如何，莫西沙星和左氧氟沙星都是活性最强的药物。莫西沙星在0.25微克/毫升时可抑制所有菌株，其效力比左氧氟沙星强8至16倍。
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