前列腺特异性抗原——并非所有升高的情况都是难治性的。
Prostate-specific antigen-all that rises is not refractory.
作者信息
Hintz B L, Van Nieuwenhuize A, Kagan A R
机构信息
Department of Radiation Oncology, Southern California Permanente Medical Group, Los Angeles, California, USA.
出版信息
Urology. 2001 May;57(5):975. doi: 10.1016/s0090-4295(01)00911-6.
After the initiation of androgen suppression in men with prostate cancer, the serum prostate-specific antigen (PSA) level generally declines. A subsequent PSA rise during that suppression usually reflects the presence of a significant component of hormonally refractory prostate cancer. We report a patient with a rising PSA level and elevated testosterone level after depot leuprolide in whom the PSA level subsequently declined with administration of bicalutamide.
在对前列腺癌男性患者开始雄激素抑制治疗后，血清前列腺特异性抗原（PSA）水平通常会下降。在该抑制过程中随后出现的PSA升高通常反映存在激素难治性前列腺癌的重要成分。我们报告了一名患者，其在使用长效亮丙瑞林后PSA水平升高且睾酮水平升高，而在给予比卡鲁胺后PSA水平随后下降。
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