Camargo E E
Division of Nuclear Medicine, Department of Radiology, School of Medical Sciences, Campinas State University (Unicamp), Campinas, Brazil.
J Nucl Med. 2001 Apr;42(4):611-23.
Structural and functional images of the brain play an important role as powerful adjuncts in the management of an increasing number of neurologic and psychiatric diseases. Brain SPECT, in particular, with perfusion agents or with neuroreceptor imaging radiopharmaceuticals, is rapidly becoming a clinical tool in many places. For many neurologic and psychiatric conditions, this imaging modality has been used in diagnosis, prognosis assessment, evaluation of response to therapy, risk stratification, detection of benign or malignant viable tissue, and choice of medical or surgical therapy. The importance of this technique in nuclear medicine today should not be overlooked, particularly in cerebrovascular diseases, dementias, epilepsy, head injury, malignant brain tumors, movement disorders, obsessive-compulsive disorder, Gilles de la Tourette's syndrome, schizophrenia, depression, panic disorder, and drug abuse.
大脑的结构和功能图像作为越来越多神经和精神疾病管理中的有力辅助手段发挥着重要作用。特别是脑单光子发射计算机断层扫描(SPECT),结合灌注剂或神经受体成像放射性药物,正在许多地方迅速成为一种临床工具。对于许多神经和精神疾病,这种成像方式已用于诊断、预后评估、治疗反应评估、风险分层、良性或恶性存活组织的检测以及药物或手术治疗的选择。当今这项技术在核医学中的重要性不应被忽视,尤其是在脑血管疾病、痴呆症、癫痫、头部损伤、恶性脑肿瘤、运动障碍、强迫症、抽动秽语综合征、精神分裂症、抑郁症、惊恐障碍和药物滥用方面。