Devous M D
Nuclear Medicine Center, University of Texas, Dallas 75235-9061.
J Clin Psychiatry. 1992 Nov;53 Suppl:13-9.
The following presentation provides an overview of SPECT brain imaging applications in both neurologic and psychiatric disorders. Specific findings in cerebrovascular disease, dementia, and epilepsy are described in order to highlight the role SPECT plays in distinguishing primary organic disease from primary psychopathology. Through case examples, new applications of three-dimensional SPECT rCBF imaging that could play a major role in defining CNS network abnormalities in major depressive disorder and obsessive compulsive disorder are elucidated. The role of network imaging analysis across groups in psychiatric subjects is contrasted to its roles in neurologic disorders. The degree to which both neurologic and psychiatric pathology seen on SPECT exceeds that observed through structural modalities is defined.
以下展示概述了单光子发射计算机断层扫描（SPECT）脑成像在神经疾病和精神疾病中的应用。描述了脑血管疾病、痴呆和癫痫的具体发现，以突出SPECT在区分原发性器质性疾病和原发性精神病理学方面所起的作用。通过病例示例，阐明了三维SPECT脑血流灌注（rCBF）成像的新应用，这些应用在确定重度抑郁症和强迫症的中枢神经系统（CNS）网络异常方面可能发挥重要作用。对比了跨组网络成像分析在精神科受试者中的作用与其在神经疾病中的作用。确定了SPECT上所见的神经和精神病理学程度超过通过结构模态观察到的程度。
