Pinilla M, Ramírez-Camacho R, Jorge E, Trinidad A, Vergara J
Department of Otorhinolaryngology, Clínica Puerta de Hierro, Universidad Autónoma, Madrid, Spain.
Otolaryngol Head Neck Surg. 2001 May;124(5):515-7. doi: 10.1067/mhn.2001.115370.
To describe a simple approach to the rat middle ear because there are few clear descriptions of this technique with minimal morbidity and mortality.
Six male Long-Evans rats were used in this study. We designed a cervical approach to the middle ear with the purpose of creating an experimental model of ossiculoplasty that permits the postoperative survival of the animal.
It was possible in all cases to visualize the majority of structures of the tympanic cavity: promontory, round window, stapedial artery, stapes, incus, and tympanic membrane. There were no cases of postoperative infection or facial paralysis.
The ventral approach to the rat middle ear is a rapid and simple technique that makes the rat the animal of choice for many otologic investigations.
描述一种针对大鼠中耳的简单方法，因为关于该技术的清晰描述较少，且发病率和死亡率极低。
本研究使用了6只雄性Long-Evans大鼠。我们设计了一种经颈部进入中耳的方法，目的是创建一个听骨成形术的实验模型，使动物术后能够存活。
在所有病例中，均有可能观察到鼓室的大部分结构：岬、圆窗、镫骨动脉、镫骨、砧骨和鼓膜。没有术后感染或面瘫的病例。
经腹侧进入大鼠中耳是一种快速且简单的技术，这使得大鼠成为许多耳科学研究的首选动物。
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