Mosin I M, Moshetova L K, Mishustin V V, Letneva I A
Vestn Oftalmol. 2001 Jan-Feb;117(1):40-3.
Clinical manifestations and course of bullous X-linked congenital retinoschisis were studied in 10 infants aged 6-18 months. Visual function was evaluated by registration of electroretinogram and visual evoked potentials. The patients were followed up for 7.65 +/- 2.51 years. Giant retinal cysts were observed in 40% patients with X-linked retinoschisis aged under 3 years. Collapse (spontaneous or after laser coagulation of the retina) of retinal cysts with formation of demarcation pigmented lines was observed in 85% children. Twenty percent patients developed hemophthalmia which was completely resorbed within 4-12 months. At the age of 6-12 years visual acuity was 0.36 +/- 0.23. The prognosis of the condition is favorable, and therefore surgical treatment or laser coagulation are not recommended in infants with bullous retinoschisis, on condition that no negative changes in the disease course are observed.
对10名6至18个月大的婴儿进行了大疱性X连锁先天性视网膜劈裂的临床表现及病程研究。通过记录视网膜电图和视觉诱发电位评估视觉功能。对患者进行了7.65±2.51年的随访。在3岁以下的X连锁视网膜劈裂患者中，40%观察到巨大视网膜囊肿。85%的儿童观察到视网膜囊肿塌陷（自发或视网膜激光凝固后）并形成分界色素线。20%的患者发生血眼，在4至12个月内完全吸收。6至12岁时视力为0.36±0.23。该病预后良好，因此，在大疱性视网膜劈裂婴儿中，若未观察到疾病进程中的负面变化，则不建议进行手术治疗或激光凝固。
