Parabiosis in Nya:NYLAR mice.

Mice from our Nya:NYLAR colony were parabiosed using the skin-to-skin or coelomic method, and more than 150 such pairs survived for periods greater than 1 mo. The oldest pair at this writing survived for 27 mo after parabiosis, which is equivalent to the normal life span of the Nya:NYLAR mouse. No evidence of parabiotic intoxication in any pair, even those kept for several mo, was noted.