Melo A L, Chamone M
Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 30161-970, Brasil.
Rev Inst Med Trop Sao Paulo. 2001 Mar-Apr;43(2):63-5. doi: 10.1590/s0036-46652001000200002.
Innate attack to Schistosoma mansoni cercariae was evaluated in irradiated mice. It was observed that 70% of the larvae from mice sacrificed one day after whole body irradiation with 400 or 800 rads were surrounded by cluster reactivities, without difference from controls. Differences were apparent on day 5 after irradiation with sub lethal (400 rads) or lethal doses (800 rads) suggesting that innate defence to infection take at least 5 days to be affected by low dose whole-body radiation.
在经辐照的小鼠中评估了对曼氏血吸虫尾蚴的先天攻击。观察到,在用400或800拉德进行全身辐照后一天处死的小鼠中,70%的幼虫被聚集反应包围,与对照组无差异。在用亚致死剂量(400拉德)或致死剂量(800拉德)辐照后第5天,差异明显,这表明对感染的先天防御至少需要5天才能受到低剂量全身辐射的影响。