Domingo C, Arcís R W, López-Macipe A, Osorio R, Rodríguez-Clemente R, Murtra J, Fanovich M A, Toledano M
Institut de Ciència de Materials de Barcelona (ICMAB-CSIC), Campus de la UAB, 08193, Bellaterra, Spain.
J Biomed Mater Res. 2001 Aug;56(2):297-305. doi: 10.1002/1097-4636(200108)56:2<297::aid-jbm1098>3.0.co;2-s.
The purpose of this study was to analyze the behavior in water as well as the mechanical and surface properties of experimental composites designed for dental restoration. Studied materials were composed of a visible-light-cured monomer mixture as a matrix (bisphenol-alpha-glycidyl methacrylate with triethyleneglycol dimethacrylate or hydroxyethyl methacrylate) and either micrometric or nanometric hydroxyapatite (HA) particles as a reinforcing filler. The surface of the filler particles was modified by using different coupling agents (citric, hydroxysuccinic, acrylic, or methacrylic acid). The hydrolytic stability of the evaluated materials was studied through elution-in-water and water-uptake tests. Mechanical and surface properties were examined through the results of flexural, hardness, and surface roughness tests. Means and standard deviations were calculated for each variable. Analysis of variance and multiple comparison tests were performed. Materials containing bisphenol-alpha-glycidyl methacrylate:triethyleneglycol dimethacrylate and micrometric-HA coated with citrate, acrylate, or methacrylate displayed the most favorable results. Improvements should be obtained by increasing the total filler amount, and by the introduction of nanometric-HA filler into a micrometric-HA reinforced composite resin system.
本研究的目的是分析用于牙齿修复的实验性复合材料在水中的行为以及其机械性能和表面性能。所研究的材料由作为基质的可见光固化单体混合物（双酚-α-甲基丙烯酸缩水甘油酯与三乙二醇二甲基丙烯酸酯或甲基丙烯酸羟乙酯）以及作为增强填料的微米级或纳米级羟基磷灰石（HA）颗粒组成。通过使用不同的偶联剂（柠檬酸、羟基琥珀酸、丙烯酸或甲基丙烯酸）对填料颗粒的表面进行改性。通过水浸出和吸水率测试研究了所评估材料的水解稳定性。通过弯曲、硬度和表面粗糙度测试结果来检测机械性能和表面性能。计算每个变量的均值和标准差。进行方差分析和多重比较测试。含有双酚-α-甲基丙烯酸缩水甘油酯：三乙二醇二甲基丙烯酸酯以及涂覆有柠檬酸盐、丙烯酸盐或甲基丙烯酸盐的微米级HA的材料表现出最有利的结果。应通过增加填料总量以及将纳米级HA填料引入微米级HA增强复合树脂体系来实现性能的提升。
