Kidwell J F, Kidwell M G
J Hered. 1979 Mar-Apr;70(2):123-6. doi: 10.1093/oxfordjournals.jhered.a109206.
The dynamics of natural selection on a lethal fourth chromosome of Drosophila melanogaster was studied in replicated half-pint bottle and cage populations over 12 generations. Population numbers fluctuated widely in all populations, but there was no association between fluctuation in numbers and change in lethal frequency. In the bottle populations the lethal heterozygote frequency decreased to a low of 0.04 to 0.05 and then increased to 0.18 to 0.30, suggesting that the selection coefficients were not constant. In the cage populations heterozygote frequency decreased to about 0.35 to 0.40. In the cage populations the data suggest that the lethal chromosome is overdominant for both viability and fertility selection.
在重复的半品脱瓶和笼养群体中，对黑腹果蝇一条致死性第四染色体上的自然选择动态进行了12代的研究。所有群体中的种群数量都有很大波动，但数量波动与致死频率变化之间没有关联。在瓶养群体中，致死杂合子频率降至0.04至0.05的低点，然后又升至0.18至0.30，这表明选择系数并非恒定不变。在笼养群体中，杂合子频率降至约0.35至0.40。在笼养群体中，数据表明致死染色体在生存力和繁殖力选择方面都是超显性的。
