McIntosh C S, Moseley I F, Fry I K, Cattell W R
Nephron. 1975;14(5):373-7. doi: 10.1159/000180467.
Studies have been carried out on the toxicity of large doses of contrast medium (Hypaque 45%) given to rats with acute renal failure induced both by mercuric chloride and by glycerol. No increase in the expected mortality of the experimental models was observed following infusion of twice the maximum clinical dose of contrast medium.
已对给氯化汞和甘油诱导的急性肾衰竭大鼠大剂量注射造影剂（泛影葡胺45%）的毒性进行了研究。在注射两倍最大临床剂量的造影剂后，未观察到实验模型预期死亡率增加。
