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采用嵌合骨板同种异体移植增强术挽救肱骨骨不连。

Salvage of humeral nonunions with onlay bone plate allograft augmentation.

作者信息

Hornicek F J, Zych G A, Hutson J J, Malinin T I

机构信息

University of Miami Tissue Bank and Department of Orthopaedics and Rehabilitation, University of Miami School of Medicine, FL, USA.

出版信息

Clin Orthop Relat Res. 2001 May(386):203-9. doi: 10.1097/00003086-200105000-00026.

Abstract

Eight women and one man were treated for 10 established diaphyseal humeral nonunions. Six patients sustained fractures in motor vehicle accidents and two patients sustained fractures in a fall. Two of the fractures were open. One patient with multiple myeloma originally was treated conservatively and received local radiation, followed by open reduction and internal plate fixation. The other patients previously were treated with fracture braces, intramedullary nails, dynamic compression plates, or a combination of these techniques. After removal of the surgical hardware and fibrous tissue at the nonunion site, stable fixation was accomplished using a cortical long bone plate allograft (femoral and tibial) or fibular shaft allograft and a dynamic compression plate. All humeral nonunions had united at an average of 2.9 months. Radiographic incorporation of the allograft cortical bone plate and fibular shaft into the host cortex occurred in all but one patient by 3 months. Graft to host junction healing was accomplished by incorporation of the cortical allograft plate into the host cortex, resulting in an increased diameter of the bone. Cortical allograft bone plates and fibular grafts provide structural and probably osteoinductive support to enhance healing of these nonunions.

摘要

8名女性和1名男性接受了治疗,他们患有10例已确诊的肱骨干骨不连。6例患者因机动车事故导致骨折,2例患者因跌倒导致骨折。其中2处骨折为开放性骨折。1例患有多发性骨髓瘤的患者最初接受保守治疗并接受局部放疗,随后进行切开复位和钢板内固定。其他患者之前接受过骨折支具、髓内钉、动力加压钢板或这些技术的联合治疗。在去除骨不连部位的手术硬件和纤维组织后,使用皮质长骨移植板(股骨和胫骨)或腓骨干移植和动力加压钢板实现了稳定固定。所有肱骨干骨不连平均在2.9个月时愈合。除1例患者外,所有患者的移植皮质骨板和腓骨干在3个月时均已与宿主皮质融合。移植骨与宿主连接部位的愈合是通过皮质同种异体移植板与宿主皮质融合实现的,导致骨直径增加。皮质同种异体骨板和腓骨移植提供了结构支持,可能还有骨诱导支持,以促进这些骨不连的愈合。

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