Fordymacka A
Zakład Badania Surowic i Szczepionek, Państwowy Zakład Higieny.
Przegl Epidemiol. 2000;54(3-4):333-41.
The aim of this study was to determine immunity against diphtheria and tetanus in various age groups and to compare it with the results of seroepidemiological studies conducted during previous 40 years. The level of diphtheria and tetanus antibody was determined by means of ELISA tests in 1534 sera obtained from persons aged 1-81 years. As elsewhere in Europe, the present study confirms the insufficiency of humoral immunity to diphtheria among Polish adults. Groups with the lowest levels of diphtheria antibody include persons aged 30-60 years (62% protected). Tetanus immunity was highest during the first three decades of life (above 90% protected), and then declined with increasing age. The comparison with results of several serologic surveys performed earlier showed gradually increasing immunity level against tetanus in all age groups.
本研究的目的是确定不同年龄组对白喉和破伤风的免疫力，并将其与过去40年进行的血清流行病学研究结果进行比较。通过ELISA试验测定了从1 - 81岁人群中获得的1534份血清中的白喉和破伤风抗体水平。与欧洲其他地方一样，本研究证实波兰成年人对白喉的体液免疫不足。白喉抗体水平最低的群体包括30 - 60岁的人（62%受到保护）。破伤风免疫力在生命的前三十年最高（超过90%受到保护），然后随着年龄的增长而下降。与早期进行的几项血清学调查结果的比较表明，所有年龄组对破伤风的免疫力水平都在逐渐提高。
