福冈县实验室数据的标准化及参考区间的建立：日本视角

Standardization of laboratory data and establishment of reference intervals in the Fukuoka Prefecture: a Japanese perspective.

作者信息

Kinoshita S, Toyofuku M, Iida H, Wakiyama M, Kurihara M, Nakahara M, Nakata M, Nakashima K, Seo S, Hosaka N, Yano J, Misumoto T, Ishihara H, Ikeda K, Tsuchihashi M, Kawashima H, Imoto Y, Imamura K, Urabe Y, Shinohara K, Ooishi K, Abe T, Jinnouchi J, Hyoudou K, Kondo S, Kobayashi T, Ono J, Hamasaki N

机构信息

The Association of Five Hospitals in Fukuoka Prefecture, Fukuoka, Japan.

出版信息

Clin Chem Lab Med. 2001 Mar;39(3):256-62. doi: 10.1515/CCLM.2001.040.

DOI:10.1515/CCLM.2001.040

PMID:11350024

Abstract

Standardization of 22 clinical chemistry analytes and five serum protein constituents has been performed in the Fukuoka Prefecture, which has a population of approximately five million. The standardization project was established to determine reference intervals for these analytes by educating physicians, medical technologists and staff of medical institutions, and by daily or monthly monitoring the use of common control samples through e-mail. Standardization extended to 97% of the institutions in the prefecture. Results for 14 of the 22 clinical chemistry analytes have become highly reliable and differences between institutions decreased. Standardization of other analytes is now in progress. Regional collaboration based on international guidelines led to a significant improvement in interlaboratory comparability. Areas where further improvements are needed have been identified.

摘要

在拥有约500万人口的福冈县，已对22种临床化学分析物和5种血清蛋白成分进行了标准化。该标准化项目旨在通过培训医疗机构的医生、医学技术人员和工作人员，并通过电子邮件每日或每月监测常用对照样品的使用情况，来确定这些分析物的参考区间。标准化覆盖了该县97%的机构。22种临床化学分析物中的14种的结果已变得高度可靠，机构间差异减小。其他分析物的标准化工作正在进行中。基于国际准则的区域合作显著提高了实验室间的可比性。已确定了需要进一步改进的领域。