Hegazy H M, Snyderman C H, Fan C Y, Kassam A B
Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Am J Otolaryngol. 2001 May-Jun;22(3):215-8. doi: 10.1053/ajot.2001.23434.
Within the head and neck region, neurilemmomas are rarely found in the nasal cavity or paranasal sinuses. A 70-year-old man presented with complaints of left-sided epiphora, rhinorrhea, epistaxis, and transient diplopia. Nasal endoscopy showed a large necrotic mass filling the left middle meatus. A computed tomography scan showed a large left ethmoid mass, with erosion of the medial wall of the orbit and the anterior cranial base. Multiple biopsies were nondiagnostic. Complete excision of the tumor was performed with endoscopic techniques. Small dural defects were repaired with a middle turbinate mucosal flap. Postoperatively, the patient was treated with nasal packing and a lumbar spinal drain. Final pathology showed a benign neurilemmoma. There has been no evidence of recurrence or cerebrospinal fluid leakage in follow-up. A review of the literature shows a similar presentation of patients with neurilemmomas of the paranasal sinuses. Bony destruction and intracranial extension is viewed. Lack of encapsulation and locally destructive growth in an otherwise histologically typical neurilemmoma should not suggest malignant potential. Many benign tumors of the paranasal sinuses with bone destruction may be removed by using endoscopic techniques.
在头颈部区域,鼻腔或鼻窦内很少发现神经鞘瘤。一名70岁男性患者出现左侧溢泪、流涕、鼻出血和短暂复视等症状。鼻内镜检查显示一个巨大的坏死肿物充满左侧中鼻道。计算机断层扫描显示左侧筛窦有一个巨大肿物,眼眶内侧壁和前颅底有侵蚀。多次活检均未明确诊断。采用内镜技术完整切除肿瘤。用中鼻甲黏膜瓣修复小的硬脑膜缺损。术后,患者接受鼻腔填塞和腰椎引流治疗。最终病理显示为良性神经鞘瘤。随访中没有复发或脑脊液漏的证据。文献回顾显示鼻窦神经鞘瘤患者有类似表现。可见骨质破坏和颅内侵犯。在组织学上典型的神经鞘瘤中,缺乏包膜和局部浸润性生长并不提示有恶性潜能。许多伴有骨质破坏的鼻窦良性肿瘤可通过内镜技术切除。