He Xindi, Wang Ying
Department of Rhinology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Ear Nose Throat J. 2023 Jul;102(7):NP364-NP368. doi: 10.1177/01455613211007947. Epub 2021 May 5.
Neurilemmoma in the nasal cavity and paranasal sinuses is very rare. The study aimed to improve the understanding of neurilemmoma in the nasal cavity and paranasal sinuses.
The clinical data of 10 patients with neurilemmoma in the nasal cavity and paranasal sinuses treated from January 2014 to June 2019 in our hospital were retrospectively studied.
There were 6 females and 4 males patients in our study. The mean age was 49.5 years (range 37-77 years), and the most common clinical symptom was unilateral nasal obstruction. The site of tumor included the nasal cavity, maxillary sinus, ethmoid sinus, and sphenoid sinus. There were 2 cases with malignant neurilemmoma. Nine patients underwent functional endoscopic sinus surgery (FESS); however, 1 patient underwent FESS combined with the lateral rhinotomy for complete resection of the tumor. Two patients with malignant neurilemmoma received postoperative radiotherapy. The mean follow-up was 3.82 years (range 2-7 years). There were no incidences of tumor recurrence during the study period.
Neurilemmoma in the nasal cavity and paranasal sinuses is a mainly benign tumor. Complete surgical excision by FESS is the only treatment option for neurilemmoma in the nasal cavity and paranasal sinuses; while malignant neurilemmoma needs postoperative radiotherapy.
鼻腔及鼻窦神经鞘瘤非常罕见。本研究旨在提高对鼻腔及鼻窦神经鞘瘤的认识。
回顾性研究2014年1月至2019年6月在我院接受治疗的10例鼻腔及鼻窦神经鞘瘤患者的临床资料。
本研究中,女性患者6例,男性患者4例。平均年龄49.5岁(范围37 - 77岁),最常见的临床症状为单侧鼻塞。肿瘤部位包括鼻腔、上颌窦、筛窦和蝶窦。有2例为恶性神经鞘瘤。9例患者接受了功能性鼻内镜鼻窦手术(FESS);然而,1例患者接受了FESS联合鼻侧切开术以完整切除肿瘤。2例恶性神经鞘瘤患者接受了术后放疗。平均随访时间为3.82年(范围2 - 7年)。研究期间无肿瘤复发情况。
鼻腔及鼻窦神经鞘瘤主要是良性肿瘤。FESS完整切除是鼻腔及鼻窦神经鞘瘤的唯一治疗选择;而恶性神经鞘瘤需要术后放疗。