Germaud P, Haloun A
Service de pneumologie, CHRU Nantes, Hôpital Laënnec, BP 1005, 44035 Nantes Cedex 01.
Rev Pneumol Clin. 2001 Apr;57(2):157-63.
Immunodepressed patients, particularly those with neutropenia or bone marrow or organ grafts, are at risk of developing nosocomial invasive pulmonary aspergilosis. The favoring factors, early diagnostic criteria and curative treatment protocols are well known. Prognosis remains however quite severe with a death rate above 50%. Preventive measures are required for the treatment of these high-risk patients and epidemiology surveillance is needed in case of aspergillosis acquired in the hospital.
免疫功能低下的患者,尤其是那些患有中性粒细胞减少症或接受骨髓或器官移植的患者,有发生医院获得性侵袭性肺曲霉病的风险。其诱发因素、早期诊断标准和治疗方案已广为人知。然而,预后仍然相当严峻,死亡率超过50%。对于这些高危患者需要采取预防措施,对于医院获得性曲霉病则需要进行流行病学监测。