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多形性横纹肌肉瘤:对放疗的反应

Pleomorphic Rhabdomyosarcoma: response to irradiation.

作者信息

Gerdes A J, Parker R G, Berry H C

出版信息

Radiol Clin (Basel). 1975;44(2):97-102.

PMID:1135403
Abstract

Although the usefulness of radiation in treatment of many embryonal rhabdomyosarcomas is recognized, the pleomorphic rhabdomyosarcomas are frequently felt to be radioresistant and thus a potentially useful mode of therapy is overlooked. There is increasing evidence in the literature to document successful local management of pleomorphic rhabdomyosarcomas with radiation. The literature is reviewed briefly and a case of rhabdomyosarcoma of the heart is reported in which radiation in doses well tolerated by normal tissues successfully controlled several local lesions at various sites until the patient's demise from widespread disease 2 years after the initial treatment.

摘要

尽管放射治疗在许多胚胎性横纹肌肉瘤的治疗中所具有的效用已得到认可,但多形性横纹肌肉瘤常被认为具有放射抗性,因此一种潜在的有效治疗方式被忽视了。文献中有越来越多的证据证明用放射治疗成功地进行了多形性横纹肌肉瘤的局部治疗。本文简要回顾了相关文献,并报告了一例心脏横纹肌肉瘤病例,在该病例中,正常组织能够良好耐受的剂量的放射治疗成功地控制了多个不同部位的局部病灶,直到患者在初始治疗两年后因疾病广泛扩散而死亡。

相似文献

1
Pleomorphic Rhabdomyosarcoma: response to irradiation.多形性横纹肌肉瘤:对放疗的反应
Radiol Clin (Basel). 1975;44(2):97-102.
2
A pleomorphic-cell sarcoma of lung with ball metastases in the heart.肺多形性细胞肉瘤伴心脏球形转移灶。
Indian J Chest Dis. 1973 Jul;15(3):240-4.
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Right atrial botryoid rhabdomyosarcoma in an adult patient with recurrent pleomorphic rhabdomyosarcomas following doxorubicin therapy.一名成年患者在接受阿霉素治疗后出现复发性多形性横纹肌肉瘤,同时伴有右心房葡萄状横纹肌肉瘤。
Ann Diagn Pathol. 2007 Aug;11(4):274-6. doi: 10.1016/j.anndiagpath.2006.03.001.
4
[Clonal analysis as a method of prognostication of tumor response to irradiation].[克隆分析作为肿瘤对放疗反应的预后评估方法]
Med Radiol (Mosk). 1986 Dec;31(12):41-7.
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Rhabdomyosarcoma of the urinary bladder with intraepithelial spread in an adult.一名成年患者膀胱横纹肌肉瘤伴上皮内播散
Arch Pathol Lab Med. 1976 Jul;100(7):395-7.
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[Botryoid sarcoma of the kidney].[肾葡萄状肉瘤]
Z Gesamte Inn Med. 1969 Oct 1;24(19):680-6.
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Rhabdomyosarcoma of the extremities in adults.
Acta Orthop Belg. 2006 Apr;72(2):199-203.
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Laryngeal pleomorphic rhabdomyosarcoma.喉多形性横纹肌肉瘤
Auris Nasus Larynx. 2007 Dec;34(4):553-6. doi: 10.1016/j.anl.2007.02.009. Epub 2007 May 3.
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[Leiomyosarcoma of the breast 16 years following successful treatment of a rhabdomyosarcoma of the orbit in childhood].[儿童期眼眶横纹肌肉瘤成功治疗16年后发生的乳腺平滑肌肉瘤]
Schweiz Med Wochenschr. 1992 Sep 5;122(36):1335-41.
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Rhabdomyosarcoma of the vagina in a postmenopausal woman: report of a case and review of the literature.一名绝经后女性的阴道横纹肌肉瘤:病例报告及文献复习
Gynecol Oncol. 1995 Sep;58(3):395-9. doi: 10.1006/gyno.1995.1251.

引用本文的文献

1
Imaging procedures in the detection of cardiac tumors, with emphasis on echocardiography: a review.心脏肿瘤检测中的成像程序,重点是超声心动图:综述
Cardiovasc Intervent Radiol. 1980;3(3):107-25. doi: 10.1007/BF02552329.